Bhidio salann disodium NADP (24292-60-2)
salann disodium fosfáit β-Nicotinamide adenine dinucleotide (salann disodium NADP) Ssaoghail
| bathar Ainm | Salann disodium fosfáit β-Nicotinamide adenine dinucleotide (salann disodium NADP) |
| Ainm Ceimigeach | Disodium NADP; Disodium fosfáit Nadide; NADP; β-NADP; Salann disodium nuclehoside triphosphopyridine; |
| Àireamh CAS | 24292-60-2 |
| InChIKey | UNRRSQIQTVFDLS-WUEGHLCSSA-L |
| SMILE | C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)([O-])OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)OP(=O)([O-])[O-])O)O)O)C(=O)N.[Na+].[Na+] |
| An ìomhaigheag airson Molecular Formula | C21H26N7Na2O17P3 |
| Cuideam Molecular | 787.37 |
| Aifreann Monoisotopic | 787.039342 g / mol |
| Rubha Fiodha | 175-178 ° C |
| Color | Buidhe |
| Stemp torage | -20 ° C |
| uisge Fuasgladh | > 50 g / L. |
| iarrtas | Coenzyme ann an oxidations aerobic agus anaerobic |
Dè a th ’ann an salann disodium fosfáit β-Nicotinamide adenine dinucleotide (salann disodium NADP)?
Tha fosfáit nicotinamide adenine dinucleotide (NADP +) na chofactor air a chleachdadh ann an ath-bheachdan anabolic. Tha salann disodium fosfáit β-Nicotinamide adenine dinucleotide na salann disodium de NADP +, is e coenzyme a tha riatanach airson coipeadh deoch làidir glùcois agus dehydrogenation oxidative stuthan eile. Agus tha e a ’nochdadh gu farsaing ann an clò beò, gu sònraichte san ae.
Tha fosfáit nicotinamide adenine dinucleotide (NADP) agus NADPH a ’cruthachadh paidhir redox. Bidh an co-mheas NADPH / NADP a ’riaghladh comas redox intracellular, gu sònraichte an fhreagairt anaerobic, mar sin a’ toirt buaidh air freagairt metabolach anns a ’bhodhaig. Is e eisimpleirean synthesis lipid agus searbhag niuclasach. Tha NADP cuideachd na paidhir coenzyme ann an grunn shiostaman cytochrome P450 agus siostaman ath-bhualadh oxidase / reductase leithid an siostam thioredoxin reductase / thioredoxin.
Tha NADPH a ’toirt seachad lughdachadh co-ionann airson ath-bheachdan biosynthetic agus a’ toirt seachad buaidhean redox gus casg a chur air puinnseanta gnèithean ocsaidean reactive (ROS), mar sin ag ath-nuadhachadh glutathione (GSH). Tha e cuideachd air a chleachdadh ann an slighean anabolic leithid synthesis cholesterol agus aigéid shailleil leudachadh slabhraidh.
A bharrachd air an sin, tha uallach air an t-siostam NADPH cuideachd airson radicals an-asgaidh a ghineadh ann an ceallan dìon tro NADPH oxidase. Tha na radicals an-asgaidh sin air an cleachdadh gus pathogens a sgrios ann am pròiseas ris an canar spreadhadh analach. Tha e co-ionnan ri lughdachadh den stòr cytochrome P450 hydroxylated aromatics, steroids, alcohols, agus drogaichean.
iarrtas de salann disodium fosfáit β-Nicotinamide adenine dinucleotide
Tha fosfáit nicotinamide adenine dinucleotide (NADP) agus NADPH a ’cruthachadh paidhir redox. Is e coenzyme a th ’ann an NADP / NADPH a bheir taic do ath-bheachdan redox tro bhith a’ giùlan electronan ann an raon farsaing de thagraidhean, gu sònraichte ath-bheachdan anaerobic leithid lipid agus synthesis nucleic acid. Tha NADP / NADPH na chàraid coenzyme ann an diofar shiostaman cytochrome P450 agus siostaman ath-bhualadh oxidase / reductase, leithid an siostam thioredoxin reductase / thioredoxin.
Is iad na h-enzyman eile a bhios a ’cleachdadh NADP mar coenzyme: Deoch làidir dehydrogenase: an urra ri NADP; ADH aroma: an urra ri NADP; Ferredoxin-NADP reductase; L-Fucose dehydrogenase; Gabase; Transferase uridyl Galactose-1-fosfáit; Glucose dehydrogenase; Dehydrogenase L-Glutamic; Glycerol dehydrogenase: NADP sònraichte; Dehydrogenase isocitric; Enzyman malic; 5,10-Methylenetetrahydrofolate dehydrogenase; Dehydrogenase 6-Phosphogluconate agus Sucinic semialdehyde dehydrogenase.
Fiosrachadh:
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